1. Calico (California Life Company)
Calico, headquartered in California, is a research and development biotech company founded by Google in 2013. Not exclusively focused on anti-aging, it has a broader mandate that includes studying the biological mechanisms of lifespan and healthspan. Calico is leading research in exploring how to counter aging and associated diseases, mainly utilising an interdisciplinary approach that incorporates advanced bioengineering, genomics, and molecular biology. The partnership with AbbVie, a Chicago-based drug company, in addition to considerable funding support from Alphabet, underpin Calico’s research operations, driving ambitious projects aimed at expanding our understanding of aging and designing innovative therapeutic strategies.
2. Unity Biotechnology
Unity Biotechnology is a renowned company in the field of longevity research, holding a primary objective to prolong human health span by developing therapeutics that slow, halt, or reverse diseases of aging. Unity focuses on senescence, a natural state where the cells lose their ability to function and regenerate which has been tied to aging symptoms and diseases. Their mainline of work involves developing small molecule medications to selectively clear senescent cells, a cutting-edge approach within longevity research. Despite some initial setbacks, Unity Biotechnology continues to remain an instrumental part of the budding field of longevity studies, driving for novel solutions to human aging.
3. BioViva
BioViva has been making headlines since its inception in 2015 due to its unconventional but innovatively compelling approach to tackle aging. The company pioneers gene therapy to combat the aging process with founder Liz Parrish herself being a testament to their groundbreaking work. She underwent her company’s experimental gene therapy to reverse aging, reporting successful results. BioViva collaborates with Integrated Health Systems, a medical group working in experimental gene therapy precision deployment, advancing its research capabilities and the efficacy of its novel gene therapies. The company remains committed to developing innovative therapies that extend healthy human lifespans and improve overall life quality.
4. Juvenescence
Established in 2017, Juvenescence is an investment firm cum biotech company devoted to longevity research, primarily focusing on therapeutic interventions that can modify aging. The company operates with a two-fold strategy- directly developing advanced therapeutics and investing in other longevity-focused biotech firms. Their direct development includes a vast range of therapies, from small molecule medicine to stem cell therapy, all targeted at modifying the aging process. Juvenescence’s investment portfolio showcases an interesting mix of companies